New drug target to battle breast cancer: study

Interesting news about targeted treatments for breast cancer. Targeted is always better than some kind of systemic nuclear bomb kind of approach. The more you can target JUST the tumor, the better off all patients will be. Here is more info on angiogenesis

Interestingly enough, it has been found that megadoses of Vitamin C actually have an antiangiogenic effect and certainly is less toxic than just about any synthetic “drug”. It may explain why large doses of Vitamin C seem to work in the fight against cancer. If I were currently fighting cancer, I would be taking large doses of Vitamin C or considering intravenous Vitamin C. I don’t think it’s recommended to remain on large doses of Vitamin C indefinitely however so you should find a naturopath or holistic practitioner who can guide you on this kind of treatment.

After some more digging, I found that there is one drug that one should avoid that are targeting angiogenesis and that drug is Avastin. Read more about why I say that here

Here is the lead article on limiting angiogenesis, which I believe is a good thing to do in fighting cancer. However I don’t believe that only drugs can provide that solution. More on this after the article.

CHICAGO (AFP) — Researchers have identified a new target for drugs to help treat the most common form of breast cancer in the developing world, a study released Thursday said.

The target is a molecular “switch” in the protein-making machinery of the cancer cell that enables a tumor to aggressively develop its own blood supply.

Women with what is called locally advanced breast cancer can develop tumors that grow anywhere from 2 centimeters to 10 centimeters in diameter.

The tumors are unusually large in many cases — they are often the size of a plum by the time they are diagnosed — due to the extremely dense network of blood vessels feeding them oxygen and nutrients.

“Our study shows that an unusual molecular switch occurs that is essential for the development of these large tumors. We think that this switch could be a target for new therapies,” said Robert Schneider, professor of molecular pathogenesis at New York University School of Medicine.

In a paper in the journal Molecular Cell, Schneider and colleagues at New York University School of Medicine describe how two proteins (4E-BP1 and eIF4G) which are present at elevated levels in locally advanced breast cancer cells selectively increase the action of certain messenger, or mRNA, molecules.

The effect of that process is to increase several fold the production of certain growth factors that drive tumor angiogenesis — the formation of the tumor’s own blood vessels.

“The switch gives us the ability to shut off production of growth factors in the tumor at their source,” said Schneider.

He said several experimental drugs were in development that would target the “switch,” with a view to curbing its growth.

If the drugs are shown to be successful in clinical trials, they could eventually be combined with a cocktail of chemotherapy drugs to eliminate the malignancy.

“This research opens new avenues for the development of targeted approaches in the treatment of one of the most common lethal forms of breast cancer worldwide,” said Silvia Formenti, a co-author and professor of radiation oncology at NYU School of Medicine.

The researchers are also hopeful that the two proteins that are over-expressed or super abundant in locally advanced breast cancer cells could serve as a biomarker for this type of cancer, making it easier to screen for.

Early indications are that it is a reliable guide to the presence of this cancer 85 percent of the time, Schneider said.

Locally advanced breast cancer accounts for about 50 percent of breast cancer cases in developing nations. Patients often have a high level of treatment failure because the cancer is so far advanced by the time it is detected.

Here is an excerpt from the News Target article on angiogenesis:

Let me lay this to you straight: you can get far more powerful anti-angiogenesis “drugs” by simply drinking broccoli juice. If you need something more powerful, take graviola tincture, which has been shown to be 10,000 times more effective than chemotherapy at shrinking tumors. If that’s still not enough, eat ten grams of chlorella and spirulina each day.

And here is more from my favorite health nut, Mike Adams, in the same article above, explaining why I am suspicious and critical of the mainstream Cancer docs and drugs:

Want to know what kind of corruption really goes on in the cancer industry and the FDA? Read Questioning Chemotherapy by Ralph Moss. Still not convinced? Check out Innocent Casualties by Elaine Feuer.

Be informed as much as possible if you find yourself in the grips of the “cancer industry”. I find myself in that position now, not for myself, but for my mother, who it is believed has a version of Pancoast’s Apical Lung Cancer. Tests are still being conducted but you better believe I’m trying to steer her AWAY from the mainstream treatments as much as possible. The hard part is getting to the place where she has faith in me and my advice.. After all, I’m not a doctor, I’m just someone who successfully fought breast cancer without chemo, radiation or surgery…